Positions open: Postdoctoral researchers (Last updated by Sep. 8, 2009 )

1. Bioinformatics.

A postdoctoroal position is currently open in Wei Wang's group at University of California, San Diego (http://wanglab.ucsd.edu) . The research is focused on inference of logic structure and characterization of dynamic features of gene regulatory networks by analyzing DNA sequence and microarray data.

The ideal candidates would possess STRONG background in (A). programming (Perl, C/C++) and (B). statistics and be familiar with algorithms used in machine learning (Bayesian network, HMM, etc.) or computational genomics (DNA sequence analysis, microarray analysis, etc.)

2. Computational Biophysics/Chemistry.

An ideal candidate should obtain Ph.D. in computational
chemistry/biophysics/biology, is highly motivated and has extensive
experience with computer modeling such as molecular dynamics simulation,
free energy calculation, force field development, homology modeling,
entropy calculation and drug design. Solid background in physics and
statistics is required. Proficient programming skills are essential.
Experience with AMBER is a plus.

Our group is interested in studying the mechanisms of protein recognition.
We are particularly interested in peptide recognition domains including
SH3 and SH2 domains. We have taken interdisciplinary approaches that
combine computer modeling and bioinformatics analysis to predict the
binding specificity of these modular domains. We have also applied the
similar approaches to predicting mutations of the HIV-1 protease that
cause drug resistance. The expected postdoc will be responsible for
developing new computational methods to tackle these challenging problems.

3. Biochemistry and Molecular Biology.

An ideal candidate should obtain Ph.D. in biochemistry/molecular biology, is highly motivated and has extensive experience with protein purification, protein binding assays, such as peptide array, protein array, biacor. Expertise in yeast biology and/or microarray/ChIP-chip/ChIP-seq is a plus.

The expected postdoc will be responsible for conducting in vitro and in vivo experiments to determine binding specificity of modular domains. There will be a close collaboration with computational biologists in the group to integrate experimental and computational analyses for reconstructing protein-protein interaction networks.

If interested, please send CV and 3 reference letters to:

Wei Wang: Email: wei-wang@ucsd.edu

We also welcome applicants with physics or biophysics background to
conduct theoretical work on analyzing network control and evolution. Such
positions will be affiliated with Center for Theoretical Biological
Physics (CTBP). The application should be submitted online at the CTBP
website (http://ctbp.ucsd.edu/research_opps.html).