Welcome to Wei Wang Group

We are interested in understanding the regulatory mechanisms underlying
cell fate decision. Especially, we take a multi-scale approach that
integrates computational and experimental investigation of epigenetic
regulation in cell fate decision from molecular level to genomic level
then to systems level. We aim to build computational and theoretical
models to uncover fundamental principles that govern cell fate decision in
development and cellular reprogramming and design strategies to
intelligently manipulate cell state.

Our research is highly interdisciplinary. The methods we use range from
molecular modeling of protein structures, to bioinformatics analysis of
epigenomic data generated by sequencing technology, to statistical
learning of genetic network, to biophysical modeling of epigenetic
landscape. The theoretical work is tightly coupled with experimental
investigation that exploits molecular biology, biochemistry, cell biology
and genomic techniques.